Hopkins Symptom Checklist – 25/37A (HSCL-25/37A)

A screening tool that assesses mental wellbeing based on five symptom dimensions—somatization, obsessive-compulsion, interpersonal sensitivity, anxiety, and depression. It is comprised of various versions, ranging from 90 to 10 items (i.e. HSCL-90, -71, -64, -58, -35, -31, -25, -20, and -10), and scaled based on four categories of responses: Not at All (1), A Little (2), Quite a Bit (3), and Extremely (4). Originally developed as a self-report tool, over time and in contexts where illiteracy predominates, HSC has been adapted for use as an interviewer administered tool. HSCL can be used for various purposes: research; epidemiological studies; clinical screening in medical and psychiatric patients, and in “healthy” populations; to measure clinical change; and to monitor and evaluate effectiveness of interventions. The HSCL25 consists of 25 items that are broken down into two sub-scales: 10 items for assessment of anxiety and 15 items that screen for depression.

Related Publications

Mels, C., Derluyn, I., Broekaert, E., & Rosseel, Y. (2010). Community-based cross-cultural adaptation of mental health measures in emergency settings: validating the IES-R and HSCL-37A in Eastern Democratic Republic of Congo. Social Psychiatry and Psychiatric Epidemiology, 45(9), 899-910.

Syed, H., Zachrisson, H., Dalgard, O., Dalen, I., & Ahlberg, N. (2008). Concordance between Hopkins Symptom Checklist (HSCL-10) and Pakistan Anxiety and Depression Questionnaire (PADQ), in a rural self-motivated population in Pakistan. BMC Psychiatry, 8(1), 59.

Mollica, R. F., McInnes, K., Sarajlić, N., Lavelle, J., Sarajlić, I., & Massagli, M. P. (1999) Disability Associated With Psychiatric Comorbidity and Health Status in Bosnian Refugees Living in Croatia. JAMA, 282(5), 433-439.

What it measures

Depression, Anxiety, Pyschosocial and emotional wellbeing, Mental Disorders


Harvard Program on Refugee Trauma


Adults and adolescents



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